Clinical Biomechanics
Institute of Sports Science and Clinical Biomechanics
55 Campusvej
DK-5230 Odense M
T: +45 6550 3448
F: +45 6550 3480
Head of Research Unit:
Professor Jan Hartvigsen
T: +45 6550 4522
E: jhartvigsen@health.sdu.dk
Secretary:
Jette Tromborg
T: +45 6550 3421
E: jtromborg@health.sdu.dk
Webpage:
www.sdu.dk/health/iob
Research areas
- Low back pain
- Cervical-spine
- Epidemiology
- Clinical tests and treatments
- Chest Pain
- Guidelines and quality assurance
Academic staff
Tom Bendix, Dr (professor)
Niels Grunnet-Nilsson, PhD (professor)
Jan Hartvigsen, PhD (professor)
Charlotte Leboeuf-Yde, PhD (professor)
Claus Manniche, Dr (professor)
René Fejer, PhD (associate professor) (on leave till 1 April 2008)
Lise Hestbæk, PhD (associate professor)
Henrik Lauridsen, PhD (assistant professor)
Cornelius Myburgh (assistant professor)
Anette Ravn Nørregaard (assistant professor)
Lotte Dyhrberg O’Neill (assistant professor)
Dorthe Johanne Olsen (research assistant)
Rikke Krüger Jensen (PhD student)
Tue Secher Jensen (PhD student)
Bendt Johansen (PhD student)
Mette Jensen Stochkendahl (PhD student)
Mads Viberg Brunse (scholarship student)
Current research projects
Low back pain (LBP) explored from several perspectives:
- Chiropractic and chronic pelvic pain (2006, Kirsten Thorhauge, Jan Hartvigsen, Henrik Wulff Christensen, Axel Forman)
- A research program is being planned in relation to the so-called “maintenance care” concept in chiropractic practice (2006, Charlotte Leboeuf-Yde, Lise Hestbæk and practising chiropractors in the Nordic countries).
- A randomized controlled clinical trial of patients at the BackCenter in Ringe (2006, Claus Manniche, Charlotte Leboeuf-Yde, Anders Svendsen, Bendt Johansen)
- A randomized controlled clinical trial of patients with Modic changes, comparing the present concept of “keep active” with a novel restitution approach (2006, Claus Manniche, Charlotte Leboeuf-Yde, Niels Wedderkopp, Rikke Krüger Jensen)
- Stem cells and degenerated lumbar discs (2005, Tom Bendix)
- Chiropractic patients in Denmark (2005, Niels Grunnet-Nilsson, Jan Hartvigsen et al.)
- A comparison of the “minimal clinically important difference” determined prospectively and retrospectively. (2005, Henrik Lauridsen, Niels Grunnet-Nilsson, Jan Hartvigsen, Claus Manniche
- What are back pain patients’ expectations to treatment? Are they in accordance with what is realistic? (2005, Henrik Lauridsen, Niels Grunnet-Nilsson, Jan Hartvigsen, Claus Manniche)
- Children/adolescents and Low Back Pain. Risk factors and risk groups for actual and/or later LBP (2005, Lise Hestbæk, Per Kjaer, Charlotte Leboeuf-Yde, Niels Wedderkopp)
- Groups at risk for Low Back Pain seen from a psycho-social perspective (2005, Lise Hestbæk, Charlotte Leboeuf-Yde)
- Subpopulations in non-specific LBP (2005, Charlotte Leboeuf-Yde)
- Forces used during spinal manipulation of the lumbar spine (2004, John Triano, Niels Grunnet-Nilsson et al.)
- Chiropractic and exercise for seniors with low back pain. A Randomised clinical trail comparing the effect of chiropractic manual treatment and home exercises versus supervised rehabilitation and home exercises versus home exercises alone in LBP patients aged 65 and older (2004, Gert Brønfort, Roni Evans, Jan Hartvigsen et al.)
- Nordic walking and low back pain. A randomised clinical trail investigating the effect of supervised Nordic walking versus unsupervised Nordic walking versus no intervention. (2004, Lars Morsø, Jan Hartvigsen, Claus Manniche, Niels Grunnet-Nilsson, Charlotte Leboeuf-Yde et al.)
- Indications of Modic changes following disc herniation being caused by a slow, anaerobic infection are tested (2004, Hanne Albert, Claus Manniche et al.)
- Modic changes and LBP in the general population – Prevalence, development over time and predictive factors (2004, Tue Secher-Jensen, Claus Manniche et al.)
- Significance of fear-avoidance behaviour. A randomized controlled trial (RCT) on a possible effect of a specific formation of a confidence-based attitude, intending to reduce pain focus, and subsequent more natural movements, versus symptom-based exercises (2003, Pia Havn Sørensen, Tom Bendix et al.)
- MRI studies on those changes causing – and those not causing - LBP/leg pain (2003, Tue Secher-Jensen, Charlotte Leboeuf-Yde, Claus Manniche et al.)
- Better backs by better beds? Waterbeds and body-contour conforming mattresses seem superior to firm mattresses as regards LBP (2002, Rasmus Fabricius, Kim Bergholdt, Tom Bendix)
- Reproduction of the biomechanics of standing is intended with spinal compression during supine MRI. Target group is spinal stenosis and soft-disc syndromes. (2002, Rasmus Madsen, Tom Bendix)
- Back and neck pain in old age. The population-based Longitudinal Study of Aging Danish Twins contain extensive interview information on health, lifestyle, physical, and mental function in persons aged 70-102. The back and neck pain studies are dealing with descriptive epidemiology, associated factors, predictors, and heritability (2002, Jan Hartvigsen, Kaare Christensen, Henrik Frederiksen, Hans Christian Petersen)
- Sciatica/disc herniation: Exercises with McKenzie-type or a trunk-stabilising program seem superior to an expectation-based attitude. Modic changes and continuous back pain seem well correlated (2001, Hanne Albert, Claus Manniche et al.)
- Epidemiology: LBP and its relation to lumbar MRI as well as physical activity etc. Two population-based cohorts of approx. 425 persons each, 13-14 and 40 years, respectively. Both are being followed for – so far – 4 years. Trans-sectional correlations and prognostic factors are identified. Modic changes and muscular fat infiltration correlate well to actual back pain (2000, Per Kjær, Charlotte Leboeuf-Yde, Tom Bendix et al.).
Neck pain/whiplash explored from the following perspectives:
- The dose-response relationship between SMT and changes in cervical range of motion - a literature review (2005, Susanne Vejsgaard Vestager, Niels Grunnet-Nilsson et al.)
- Chiropractic and exercise for seniors with neck pain. A Randomised clinical trail comparing the effect of chiropractic manual treatment and home exercises versus supervised rehabilitation and home exercises versus home exercises alone in neck pain patients aged 65 and older (2004, Gert Brønfort, Roni Evans, Jan Hartvigsen et al.)
- Neck pain – prevalence and heredity vrs. environmental factors. A popupulation-based study on significance and prognostic indicators as well as a twin study are carried out (2003, René Fejer, Jan Hartvigsen)
- Prognostic factors of early MRI, eye-movements and bone scintigrafi following whiplash injury (2000, Alice Kongsted, Tom Bendix)
- RCT on light exercises, ‘live as usual’ of stiff neck collar in the acute stage of whiplash-induced neck/arm pain/headache is being carried out (2000, Alice Kongsted, Tom Bendix).
Evaluation of clinical tests:
- Validation of patient specific function scale in patients with thoracic pain (2005, Louise Johannesen, Susanne Helgeson, Henrik Lauridsen)
- Responsiveness of clinical outcome measures. Several of the most common used LBP-variables – Roland Morris-, SF36- and Oswestry Questionaires etc. – are evaluated for clinical significance in relation to treatment effect (2004, Henrik Lauridsen, Niels Grunnet-Nilsson, Jan Hartvigsen, Claus Manniche)
- Translation and validation of the Bournemouth Questionnaire (BQ) in Danish. The BQ is a validated questionnaire assessing pain, physical functional status, social functional status, depression, and coping in LBP patients. (2003, Jan Hartvigsen)
- The relative sensitivity of three different types of clinical outcome measures in chiropractic patients with low back pain (2003, Lene Hare-Mortensen, Henrik Lauridsen, Niels Grunnet-Nilsson)
- Manual examination of the spine: Reproducibility of manual palpation. A systematic, critical literature review (2002, Mette Jensen Stochkendahl, Henrik Wulff Christensen, Jan Hartvigsen, Gert brønfort, Werner Vach, Mitchell Hass).
Thoracic spine pain and chest pain:
- CARPA, Non-cardiac chestpain Treatment and Evaluation Study (2006, Mette Jensen Stochkendahl)
- Musculoskeletal chest pain – diagnosis and treatment, a PhD project. A description of patients received at an acute chest pain clinic at a university hospital and a randomised clinical trail in primary sector patients (2004, Mette Jensen Stochkendahl, Jan Hartvigsen, Henrik Wulff Christensen, Poul Flemming Høilund-Carlsen, Werner Vach, Torben Haghfelt).
Qualitative research:
- The integration of allopathic and chiropractic education in Denmark (2006, Cornelius Myburgh, Niels Grunnet-Nilsson)
- Non-invasive physical treatments for chronic/recurrent headache (1998, Gert Brønfort, Niels Grunnet-Nilsson, Mitchell Haas, Roni Evans, Charles H. Goldsmith, William J.J. Assensdelft, Lex M. Bouter).
Publications
Selected publications:
Kjær P, Leboeuf-Yde C, Korsholm L, Solgaard Sorensen J, Bendix T. Magnetic resonance imaging and low back pain in adults: A diagnostic imaging study of 40-year-old men and women. Spine 2005; 30: 1173-80.
Bendix T. Lumbar disc herniation - definition, natural course, history and physical examination. In: Herkowitz HN, Dvorak J, Bell GR, Nordin M, Gross D, eds. The Lumbar Spine / International Society for the study of the Lumbar Spine. London: Lippincott Williams & Wilkins, 2004; 3rd ed.: 399-406.
Hestbæk L, Iachine I, Leboeuf-Yde C, Kyvik K, Manniche C. Heredity of Low Back Pain in a Young Population: A Classical Twin Study. Twin Research 2004; 7: 16-26.
Hestbæk L, Leboeuf-Yde C, Manniche C. Low back pain: what is the long-term course? A review of studies of general populations. Eur Spine J. 2003; 12(2): 149-65.
Manniche C, Ejstrup L, Leboeuf-Yde C. Rygsmerter. Medicinsk Kompendium. København: Forlaget Munksgaard, 2003: 527-41.
Recent publications
Publication profile:
Syddansk Universitet, Årsberetning 2006, p. 124 (.pdf)
Syddansk Universitet, Årsberetning 2005, p. 30 (.pdf)
Syddansk Universitet, Årsberetning 2004, p. 31 (.pdf)
Syddansk Universitet, Årsberetning 2003, p. 25 (.pdf)
Syddansk Universitet, Årsberetning 2002, p. 84 (.pdf)
Syddansk Universitet, Årsberetning 2001, p. 69 (.pdf)
Syddansk Universitet, Årsberetning 2000, p. 154 (.pdf)
Syddansk Universitet, Årsberetning 1999, p. 149 (.pdf)
Other presentations
Publications:
Hartvigsen J. Ondt i ryggen … Educational booklet published by the Danish Pro Chiropractic Association, 2006.
Popular lectures:
Jan Hartvigsen:
- Forskningshandlingsplanen for Nordisk Institut for Kiropraktik 2005-10. Foreningen af Kiropraktorer i Region Syddanmark. 17 May 2006.
- Ny viden om smerter i lænderyggen. Temadag om evidensbaseret rygbehandling i Københavns Kommune. 16 May 2006.
- Forskningshandlingsplanen for Nordisk Institut for Kiropraktik 2005-10. Foreningen af Kiropraktorer i Frederiksborg Amt. 2 May 2006.
- Forskningshandlingsplanen for Nordisk Institut for Kiropraktik 2005-10. Foreningen af Kiropraktorer i Region Midtjylland. 5 April 2006.
- Forskningshandlingsplanen for Nordisk Institut for Kiropraktik 2005-10. Foreningen af Kiropraktorer i Storstrøms Amt. 3 March 2006.
- Research and chiropractic – why? Principal speech at graduation ceremony. University of Southern Denmark. 31 January 2006.
Media appearances:
Jan Hartvigsen:
- Skader i haven. Interview, P4 Eftermiddag. 30 May 2006.
- Sygdomme som ikke burde eksistere. Interview, Krause på tværs, DR P1. 8 February 2006.
PhD
Recent PhD projects:
Henrik Hein Lauridsen:
Supervisor: Professor, PhD Niels Grunnet-Nielsson
Responsiveness of clinical outcome measures. An investigation of low back pain patients seen in the primary and secondary sectors of the Danish health-care system
(27 August 2007)
René Fejer:
Supervisor: Associate professor, PhD Kirsten Ohm Kyvik
Neck pain - Prevalence, genetic and environmental factors
(21 September 2006)
Alice Kongsted:
Supervisor: Professor, Dr Tom Bendix
Acute Whiplash Injury: The effect of early interventions and the predictive value of smooth pursuit eye movement testing
(7 October 2005)
Per Kjaer:
Supervisor: Professor, Dr Tom Bendix
Low Back Pain - relation to lumbar spine abnormalities as identified by Magnetic Resonance Imaging
(13 January 2005)
Hanne Albert:
Supervisor: Professor, Dr Claus Manniche
A Clinically controlled trial of conservative treatment of patients with low back pain and sciatica
(10 September 2004)
Lise Hestbæk:
Supervisor: Professor, PhD Charlotte Leboeuf-Yde
The natural course of low back pain and early identification of high-risk populations
(19 June 2003)
Current PhD projects
Innovation - Centres and programmes
Centres:
- Clinical Locomotion Science is a research centre established in 2005 in a collaboration between the University of Southern Denmark, the County Hospitals of Funen and the Nordic Institute of Chiropractic and Clinical Biomechanics. The partners in Clinical Locomotion Science produce original research, synthesize evidence and implement research findings in educational and patient related contexts in relation to disorders of the human musculoskeletal system, www.cls.sdu.dk.
National and international research programmes:
Available methodologies, techniques and facilities
- MRI
- Epidemiology
- Randomised clinical trials
- Eye movements
- Spinal mobility
- Questionnaire evaluation.
Last update: 15 January 2008, secretary jtromborg@health.sdu.dk
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